| Comments |
Restriction digests of the clone give the following sizes: EcoRI--32.5, 10.5, 1.5; BamHI--22.0, 15.0, 8.0, 7.0, 1.4; PstI--22.5, 6.0, 3.1, 2.5, 2.1, 1.75, 1.25, 1.2, 1.1, 0.9, 0.7, 0.6; HindIII--24.8, 10.0, 8.3, 4.8; SmaI--23.0, 9.0, 5.6, 2.4, 1.1, 1.0. Contains the complete coding sequence, with 5' and 3' untranslated regions. A 0.35 kb PvuII/XbaI fragment from the insert detects a genomic PstI fragment of 8.0 kb. |
| References |
Wozney JM, et al. Novel regulators of bone formation: molecular clones and activities. Science 242: 1528-1534, 1988. PubMed: 3201241
Tabas JA, et al. Bone morphogenetic protein: chromosomal localization of human genes for BMP1, BMP2A, and BMP3. Genomics 9: 283-289, 1991. PubMed: 2004778
Wang EA, et al. DNA sequences encoding osteoinductive products. US Patent 5,013,649 dated May 7 1991
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