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Streptomyces peucetius Grein et al.
Streptomyces peucetius Grein et al.
規格:
貨期:
編號:B186466
品牌:Mingzhoubio

標準菌株
定量菌液
DNA
RNA

規格:
凍干粉
斜面
甘油
平板


產品名稱 Streptomyces peucetius Grein et al.
商品貨號 B186466
Strain Designations IMRU 3868 [JCM 9920]
Application
Produces FCE 21424
Produces FCE 24366
Produces FCE 24367
Produces anthracyclines
Produces daunorubicin daunomycin
Produces antineoplastic agents FCE 21424, FCE 24366 and FCE 24367
Biosafety Level 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Product Format freeze-dried
Preceptrol® no
Type Strain yes (type strain)
Comments
Protease activity
Synthase genes for daunorubicin/doxorubicin
Medium ATCC® Medium 196: Yeast malt extract agar
Growth Conditions
Temperature: 26.0°C
Name of Depositor RE Gordon
Chain of Custody
ATCC <<--RE Gordon<<--A. DiMarco
References

Dekleva ML, et al. Nutrient effects on anthracycline production by Streptomyces peucetius in a defined medium. Can. J. Microbiol. 31: 287-294, 1985. PubMed: 3859358

Cassinelli G, et al. New biosynthetic anthracyclines related to barminomycins incorporating barbiturates in their moiety. J. Antibiot. 43: 19-28, 1990. PubMed: 2307627

Gibb GD, Strohl WR. Physiological regulation of protease activity in Streptomyces peucetius. Can. J. Microbiol. 34: 187-190, 1988. PubMed: 3042115

Stutzman-Engwall KJ, Hutchinson CR. Multigene families for anthracycline antibiotic production in Streptomyces peucetius. Proc. Natl. Acad. Sci. USA 86: 3135-3139, 1989. PubMed: 2717612

Rajgarhia VB, Strohl WR. Minimal Streptomyces sp. strain C5 daunorubicin polyketide biosynthesis genes required for aklanonic acid biosynthesis. J. Bacteriol. 179: 2690-2696, 1997. PubMed: 9098068

Furuya K, Hutchinson CR. The DnrN protein of Streptomyces peucetius, a pseudo-response regulator, is a DNA-binding protein involved in the regulation of daunorubicin biosynthesis. J. Bacteriol. 178: 6310-6318, 1996. PubMed: 8892835

Lomovskaya N, et al. The Streptomyces peucetius drrC gene encodes a UvrA-like protein involved in daunorubicin resistance and production. J. Bacteriol. 178: 3238-3245, 1996. PubMed: 8655504

Skerman VB, et al. Approved lists of bacterial names. Int J Syst Bacteriol 30: 225-420, 1980.

type strain

type strain

Cross References

Nucleotide (GenBank) : M80237 S.peucetius DnrI and DnrJ genes, complete cds.

Nucleotide (GenBank) : L76359 Streptomyces peucetius daunorubicin resistance protein (drrC) gene, complete cds.

Nucleotide (GenBank) : L13453 Streptomyces peucetius (clone pWHM902) carminomycin 4-O-methyltransferase gene, complete cds.

Nucleotide (GenBank) : L47164 Streptomyces peucetius dnrP gene, partial cds, glycosyl transferase (dnrS) and dnrQ genes, complete cds.

Nucleotide (GenBank) : L35560 Streptomyces peucetius daunorubicin-doxorubicin polyketide synthase (dnrH, dpsA-dpsF) genes, ORF5 and ORF8, complete cds.

Nucleotide (GenBank) : L47163 Streptomyces peucetius glucose-1-phosphate thymidylyltransferase (dnrL) gene, complete cds and truncated dnrM gene, complete cds.

Nucleotide (GenBank) : U18082 Streptomyces peucetius daunorubicin and doxorubicin resistance determinant (drrAB) gene, partial cds, and aklavinone C-11 hydroxylase (dnrF) gene, complete cds.

Nucleotide (GenBank) : L37338 Streptomyces peucetius TDP-D-glucose-4,6-dehydratase (dnrM) gene, 3' end, regulatory protein (dnrN) gene, complete cds, and repressor protein (dnrO) gene, complete cds.

Nucleotide (GenBank) : L40425 Streptomyces peucetius methylaklanonic acid cyclase (dnrD), carminomycin o-methyltransferase (dnrK) and 10-carbomethoxy-13-deoxycarminomycin esterase (dnrP) genes, three complete cds's.

Nucleotide (GenBank) : AF006633 Streptomyces peucetius daunosamine biosynthesis genes, putative flavoprotein (dnmZ), putative epimerase (dnmU) and thymidine diphospho-4-keto-2,3,6-trideoxyhexulose reductase (dnmV) genes, complete cds.

Nucleotide (GenBank) : U77891 Streptomyces peucetius daunorubicin C-14 hydroxylase (doxA), doxorubicin biosynthesis enzyme DnrV (dnrV), daunorubicin C-13 ketoreductase (dnrU), daunorubicin acyl carrier protein (dpsG), daunorubicin biosynthesis enzyme (dpsH), doxorubicin

梅經理 17280875617 1438578920
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