| Comments |
Restriction digests of the clone give the following sizes (kb): BamHI--5.4, 2.8 (doublet); HindIII--4.2, 3.1, 2.3, 1.1, 0.75; PstI--4.2, 3.8, 3.1; EcoRI--4.5, 3.5, 2.7, 0.44; SmaI--5.8, 2.5, 1.73. The insert was subcloned from EMBL3-S2 and contains 2.8 kb of the PCNA promoter and the full length human PCNA gene. There are extensive sequence similarities among introns and between introns and exons. |
| References |
Travali S, et al. Structure of the human gene for the proliferating cell nuclear antigen. J. Biol. Chem. 264: 7466-7472, 1989. PubMed: 2565339
Ku DH, et al. Human gene for proliferating cell nuclear antigen has pseudogenes and localizes to chromosome 20. Somatic Cell Mol. Genet. 15: 297-307, 1989. PubMed: 2569765
Renato Baserga, personal communication
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