| Comments |
Restriction digests of the clone give the following sizes (kb): EcoRI--19.8, 13.8, 11.5, 2.2; XhoI--uncut; BamHI--21.0, 11.0, 7.8, 6.6, 6.0, 4.3, 2.0; XbaI--26.1, 20.0, 5.4, 0.95; KpnI--27.5, 17.0, 3.8, 1.7. The MspI polymorphisms have a combined PIC value of 0.52 and a combined heterozygosity of 64%. Enzyme(s) not detecting polymorphism: BamHI, BglII, EcoRI, HindIII, HincII, PstI, TaqI (panel of 5 individuals). |
| References |
Schumm JW, et al. Identification of more than 500 RFLPs by screening random genomic clones. Am. J. Hum. Genet. 42: 143-159, 1988. PubMed: 2892396
Donis-Keller H, et al. A genetic linkage map of the huma genome. Cell 51: 319-337, 1987. PubMed: 3664638
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