Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Product Format
frozen
Storage Conditions
vapor of liquid nitrogen
Comments
Negative for ALV. The original member of the rel oncogene family, 'v-rel', is found in REV-T. Virus may lose tumorigenicity on tissue culture passage. TC propagated material contains helper viruses.
Effect on Host
Yes, in vitro effects: Cytopathic effects (moderate) and immunofluorescent antigen in tissue culture
Death in animals, moderate CPE and ????? immunofluorescent ag in vitro
Yes, in vivo effects: Death in animals
Recommended Host
chicken embryo fibroblasts; chicken
Host of Choice: CEF TC, C
Host Range: CEF TC, C, turkey quail, duck and other avian species
chicken embryo fibroblasts in tissue culture; chicken bone marrow cells; chicken; turkey; quail; duck; other avian species
Growth Conditions
Duration: 8 days
Name of Depositor
RL Witter
Special Collection
ATCC
References
Thielen GH, et al. Biological studies with RE virus (strain T) that induces reticuloendotheliosis in turkeys, chickens, and Japanese quail. J. Natl. Cancer Inst. 37: 731-743, 1966. PubMed: 4289067
Purchase HG, et al. A new group of oncogenic viruses: reticuloendotheliosis, chick syncytial, duck infectious anemia, and spleen necrosis viruses. J. Natl. Cancer Inst. 51: 489-499, 1973. PubMed: 4358134
Witter RL, et al. Peripheral nerve lesions similar to those of Marek's disease in chickens inoculated with reticuloendotheliosis virus. J. Natl. Cancer Inst. 45: 567-577, 1970. PubMed: 5002007
