| Comments |
Restriction digests of the clone give the following sizes (kb): EcoRI--20.0, 11.0, 6.6, 3.6, 3.0; HindIII--20.0, 10.0, 5.4, 3.5, 2.7, 1.4; KpnI--18.0, 11.0, 9.0, 3.0, 2.0, 1.4; PvuI--17.0, 13.0, 7.4, 4.8, 2.3; SacI-->23.0, 6.2, 5.0, 3.8. The BglI polymorphisms have a combined PIC value of 0.81 and a combined heterozygosity of 81%. |
| References |
Schumm JW, et al. Identification of more than 500 RFLPs by screening random genomic clones. Am. J. Hum. Genet. 42: 143-159, 1988. PubMed: 2892396
Donis-Keller H, et al. A genetic linkage map of the huma genome. Cell 51: 319-337, 1987. PubMed: 3664638
Kazazian HH Jr., et al. Characterization of a spontaneous mutation to a B-thalassemia allele. Am. J. Hum. Genet. 38: 860-867, 1986. PubMed: 3014870
Knowlton RG, et al. Use of highly polymorphic DNA probes for genotypic analysis following bone marrow transplantation. Blood 68: 378-385, 1986. PubMed: 3524708
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