Produces 20 alpha-hydroxysteroid dehydrogenase, 7 beta-dehydrogenase, 7 alpha-dehydroxylase, bile acid, and the steroid desmolase
Isolation
Human feces, New York
Biosafety Level
1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Product Format
freeze-dried
Storage Conditions
Frozen: -80°C or colder Freeze-Dried: 2°C to 8°C Live Culture: See Propagation Section
Preceptrol®
no
Genome Sequenced Strain
Yes
Type Strain
yes
Comments
This strain has been sequenced as a reference genome for the NIH Human Microbiome Project
Medium
ATCC® Medium 2107: Modified Reinforced Clostridial
ATCC® Medium 260: Trypticase soy agar/broth with defibrinated sheep blood
Growth Conditions
Temperature: 37°C
Atmosphere: Anaerobic
Name of Depositor
LV Holdeman
Chain of Custody
ATCC <-- LV Holdeman <-- V.D. Bokkenheuser 19
References
Krafft AE, Hylemon PB. Purification and characterization of a novel form of 20alpha-hydroxysteroid dehydrogenase from Clostridium scindens. J. Bacteriol. 171: 2925-2932, 1989. PubMed: 2722736
Morris GN, et al. Clostridium scindens sp. nov., a human intestinal bacterium with desmolytic activity on corticoids. Int. J. Syst. Bacteriol. 35: 478-481, 1985.
