| Applications |
This line was derived from S49.1 (ATCC TIB-28) by selecting for resistance to 10 mM thymidine and 0.1 mM 5-bromo-2'-deoxyuridine. Like the parent line, the cells are sensitive to 0.001 mM cortisol (hydrocortisone), 5 mcg/ml phytohemagglutinin and 0.01 mM 6-thioguanine. Tested and found negative for ectromelia virus (mousepox). |
| Comments |
This line was derived from S49.1 (ATCC TIB-28) by selecting for resistance to 10 mM thymidine and 0.1 mM 5-bromo-2'-deoxyuridine. Like the parent line, the cells are sensitive to 0.001 mM cortisol (hydrocortisone), 5 mcg/ml phytohemagglutinin and 0.01 mM 6-thioguanine. Tested and found negative for ectromelia virus (mousepox). |
| References |
Ralph P, et al. Independence of theta and TL surface antigens and killing by thymidine, cortisol, phytohemagglutinin, and cyclic AMP in a murine lymphoma. Biochem. Biophys. Res. Commun. 55: 1085-1091, 1973. PubMed: 4358928
Horibata K, Harris AW. Mouse myelomas and lymphomas in culture. Exp. Cell Res. 60: 61-77, 1970. PubMed: 5439579
Schiller JG, et al. Glucocorticoid receptors in lymphoma cells in culture: relationship to glucocorticoid killing activity. Science 171: 189-191, 1971. PubMed: 4395230
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